The patient's review of systems was otherwise negative and she stated that she felt like she was in excellent health other than this current presentation of thrombocytopenia. On questioning dietary habits and history the patient reported that six-eight weeks prior to this presentation she was taking Plexus-SLIM® as a weight loss supplement. The patient’s medications were Apri® (desogestrel and ethynyl estradiol) and Metformin daily. Additionally, she stated that she had never had easy bruising or a confirmed episode of thrombocytopenia before. The patient denied any pertinent family and surgical history. The patient endorsed mild bleeding of the gums after brushing her teeth over the past three weeks as well as two episodes of epistaxis during this same time period. She was immediately sent for hospital evaluation and admission. After complete blood count (CBC) and comprehensive metabolic panel (CMP) were completed, the patient was subsequently found to have a platelet count of eight-thousand and mild transaminitis with alanine aminotransferase (ALT)/ aspartate aminotransferase (AST) of 99 and 63 respectively. Ī 30-year-old female, with a past medical history of polycystic ovarian syndrome and hypertension, presented to an internal medicine clinic for a chief complaint of “easy bruising” for approximately three weeks in duration. Plexus contains both garcinia cambogia fruit extract, and chromium polynicotinate, both compounds hypothesized to be a potential cause of thrombocytopenia. This supplement is a non-FDA approved drug marketed for weight loss and appetite suppression. Here we report a related instance of a proposed dietary cause of DITP caused by the use of a common weight loss supplement, Plexus®. Incidentally, it is also available in tonic water, a liquid drink commonly consumed. Most notable are the reports of quinine-induced thrombocytopenia, a compound derived from the Cinchona trees of Peru, used for the treatment of malaria and babesiosis. While being a relatively rare cause of ITP, dietary consumption of certain compounds is a well-reported precipitating event. Of specific interest to this report are the documented cases of secondary ITP induced by dietary compounds, categorized as drug-induced ITP (DITP). With studies estimating the incidence of the disease to be approximately eight per 100,000 in the United States, ITP is a relevant disease process that is routinely discovered and discussed in the hospital setting. Additionally, multiple mechanisms have been proposed for secondary ITP, defined by the destruction of platelets in the absence of primary autoimmune autoantibody production. The subsequent splenic destruction of autoantibody tagged platelets is accordingly the cause of the thrombocytopenia. Although the pathogenesis of the disease is not fully understood, it has been proposed that the pathogenic production of autoantibodies to the patient’s platelet membrane glycoproteins, specifically GPIIb/IIIa, is the primary pathologic feature of the disease. Primary immune thrombocytopenic purpura (ITP) is an autoimmune disease caused by autoantibodies directed against platelet antigens, characterized by thrombocytopenia and increased risk of bleeding.
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The cookie is used to store the user consent for the cookies in the category "Other. This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary". The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". The cookie is used to store the user consent for the cookies in the category "Analytics". These cookies ensure basic functionalities and security features of the website, anonymously. Necessary cookies are absolutely essential for the website to function properly. Porridge and Weetabix contain up to 10 times more fibre and just a fraction of the salt and sugar in other best-sellers. Which is better for you porridge or Weetabix?ĬHOOSE to start your day wisely – as some “healthy” cereals have far more salt than their breakfast rivals. How many calories are in 3 Weetabix with full fat milk?Ĭereals ready-to-eat, WEETABIX WHOLE WHEAT CEREAL Research, however, supports the opposite. Full-fat milk is better for weight loss: Most people steer clear of full-fat milk, believing the fat and calories contained in the milk will lead to weight gain. In fact, there is scanty evidence available to link dietary cholesterol with blood cholesterol. However, balance is the key, and you can have too much of a good thing.Īs you can see, Weetabix is low calorie but, that fibre we keep talking about the 3.8g per 2 biscuit serving that is very filling and the fuller you feel, the more likely it is that you’ll stick to your diet plan. It provides an excellent breakfast and an ideal snack any time of the day, including bedtime. Weetabix is an ideal food from a healthy eating point of view as it is low in fat, high in fibre and low in sugar. To increase milk intake, drink a glass with meals or try mixing it into other dishes, including eggs, oatmeal, and smoothies. So, if your goal is weight gain, whole milk may be your best choice. Is whole milk or 2 better for weight gain? Weetabix & Milk 2 weetabix with 150ml semi-skimmed milk (38g) How many calories are in 1 Weetabix with whole milk? Once in control of the mobile number, thieves can request any second factor that is sent to the newly activated device, such as a one-time code sent via text message or or an automated call that reads the one-time code aloud. Porting a number to a new provider shuts off the phone of the original user, and forwards all calls to the new device. “We have been encouraging them to add a port validation feature, if they’ve not already done so.”Ĭrooks typically use phony number porting requests when they have already stolen the password for a customer account (either for the mobile provider’s network or for another site), and wish to intercept the one-time password that many companies send to the mobile device to perform two-factor authentication. “We have been alerting customers via SMS that our industry is experiencing a phone number port out scam that could impact them,” T-Mobile said in a written statement. Unauthorized mobile phone number porting is not a new problem, but T-Mobile said it began alerting customers about it earlier this month because the company has seen a recent uptick in fraudulent requests to have customer phone numbers ported over to another mobile provider’s network. Tips for minimizing the risk of number porting fraud are available below for customers of all four major mobile providers, including Sprint and Verizon. T-Mobile, AT&T and other mobile carriers are reminding customers to take advantage of free services that can block identity thieves from easily “porting” your mobile number out to another provider, which allows crooks to intercept your calls and messages while your phone goes dark. It is also making use of machine learning (I presume using Apple’s new machine learning libraries in High Sierra) to do interesting things, such as automatically naming layers based on the content of the layer. (On the other hand, I’m sure some people are thinking “not another RAW editor” !!!) I would imagine it uses Apple’s Core Image for its raw engine. They go into quite a bit of detail about their raw engine, so it will be interesting to see how it compares. I’m not sure i this means you can apply masks and so on to a raw file too, but I presume it does. It has a feature called “RAW Layers” which means you can have multiple raw images in a document, in layers, all the file retaining their “rawness” and keeping the edits non destructive. Which leads me to the second thing that caught my eye… Image editing functions are also non destructive. Think of it like having Photoshop’s smart layers, but always on, and without the limitations. In particular this is very useful when arranging layers in your document. The application does a lot of this already, but they have made it a key point of the new one. It looks really nice, and it has some nice features too.įor a start it try to keep everything non-destructive. Pixelmator Pro seems to throw that out the window and create a whole new style of application. For some time now, any of the “photoshop competitors” that have been released (including the current version of Pixelmator) have seemed to try and create a better version of Photoshop, and they have stuck to the Photoshop style of interface. What has me really excited though, is that it’s a completely new style of interface. If you feel so inclined to respond, please imagine that you probably need to either explain things to me like Im 6 yrs old or tell me a broad area of car diagnostics to do my own research. By actively helping the moderators with this you ensure that the r/Cartalk community continues to be a worthwhile and knowledgeable resource for car repairs.įull disclosure, I am very green and know very little about car mechanics. Report posts and comments that fall outside the guidelines. If you do not take the time to include this basic information your post may be removed until it is revised. By making a good attempt to narrow down where and what may be causing the problem you save those trying to help many steps in diagnosing the problem.** Be sure to also include the year, make, model and engine size of you car in your title, along with your main issue.** For example "2003 Ford Crown Victoria 4.6L exhaust manifold bolts rusted off" would be an acceptable post title. Take pictures, crawl under the car, look under the hood. Attempt to investigate the repair issue on your own. Have as much information as you can about the issue before posting. If you still aren't sure about something you are about to post, please look at the links down below for other subreddits that might be better suited for your question, or message the moderators.* Most repairs have already been covered multiple times somewhere in great depth that will satisfy your needs. * Remember that posting here is not a substitute for using Google. Some examples of things that are NOT GENERALLY ALLOWED: links to articles or videos that are for profit, professional-level body work repairs, detailing or cleaning questions, aftermarket car stereo questions ( /r/CarAV), car reviews ( r/Cars), new & used vehicle recommendations, price comparisons for tires, stereos, exhaust, etc, and especially questions regarding cost of repairs or the legitimacy of a mechanic's quote. It will let you read and reset the codes. You can get a code reader from Amazon that works with 1996 and up vehicles for about $15. They will have a letter followed by four numbers, for example "P1234". You can have codes read at Auto Zone, Pep Boys, O'Reilly's, etc., for free in most states. Get OBD codes! If you have a Check Engine (CEL) or Service Engine (SEL) Soon light on, get the codes read and have them available if possible befoer posting. We're here to help you, but not to assist in negotiating with mechanics (this is business/life advice, not repair advice) or to tell you what car you should buy. Also respect those that take the time to answer questions and remember that many are professional mechanics, who normally get paid very well to diagnose automotive repairs. Treat those asking for help with respect, and answer without bias toward them, their situation, or their knowledge (or lack thereof) about the repair issues. Post disappeared? Read the following guidelines, and if you think it still is relevant, message the mods to free it from the spam filter. We look forward to helping everyone with their car repairs and questions, but please take the time to read this sidebar. R/Cartalk is the original Reddit auto repair community, with over 650,000 subscribers and growing. MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEAtOZGsX7UoDPuxCfEuw4i MESSAGE: Keywords has been found: offset = +0x01647035. 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The controls feel awkward as well and I don’t think the person who decided on the button configuration has played a shooter for more than an hour. There is a slightly steep difficulty curve and you unlock the ability to play on Hard (I’m talking about difficulty) after completing a particular mission. It is a third person shooter and your aim is to take out the zombies that spawn. Gameplay is split across various missions that are great for pickup and play while taking a break from something more involving. The story is throwaway and while there are some cutscenes and dialogue sections, there’s nothing to write home about. Set in a zombie apocalypse, a school sees only five girls survive and it is their aim to destroy the zombies. While I do enjoy playing Japanese games, there are some localizations that have me signing up for a review as soon as they are announced. Unfortunately the wait was not worth it here.Īs the name suggests, you play as school girls who are fighting zombies. The wait for a localization grew painful and Aksys swooped in to save the day. Ever since School Girl/Zombie Hunter was shown off at Tokyo Game Show, I was interested. I even imported Natsuiro High School (Don’t google this at work) and found it hilarious. While the Senran Kagura games are popular for obvious reasons, I enjoyed Onechanbara because it played like a B grade action movie, but one that was less fun than Earth Defense Force. Tamsoft has developed a few games I have enjoyed over the years like Senran Kagura: Estival Versus and Onechanbara Z2: Chaos. The eighth achievement requires you to achieve Mars Ending.(Getting Singularity in another simulation) The seventh achievement requires you to restart the simulation.
Audio Hijack 3.6.1 Mac Edition is the multi-recording app that lets you record the audio from several platforms in an. Further, Audio Hijack MAC Torrent will allow you to record any application's audio, from Internet streams to. Experiment to get the exact audio setup you desire when recording voice chat audio.NMac Ked | Audio Hijack drastically changes the way you use audio on your computer, giving you the freedom to listen to audio when you want and how. This modification will result in the Recorder block capturing all audio (both your local mic and the remote caller) to both the left and right channels.Īudio Hijack's flexible design allows you to customize your audio capture and recording to get what you want. An additional Channels block has been added, and set to Mono. Here, only one small change has been made on the upper branch of this layout. This session will record call audio to one file with merged audio. In this example, we’ll show you how to record audio from all participants to both channels of a single file. Record a single file with merged audioīy default, the Voice Chat template places audio from local microphones onto the left channel, and remote audio onto the right channel. Thanks to the already configured Channels block, which was copying the remote audio to both channels, a stereo file containing just the remote audio will be created. Here, an additional Recorder block has been added. The lower branch of this layout will be used to record just the caller’s audio. As a result, the Recorder block will record just that microphone audio to one stereo file. Adjusting this block to use the Copy Left setting causes the local microphone audio (which was split to the left channel by the Application block) to be copied to the right channel. In the upper branch of this layout, an additional Channels block has been added. This session is configured to record call audio to two separate audio files. This example shows you how to record audio from your microphone into one file, with incoming audio from your callers going to a second file. The following examples modify the Voice Chat template to produce different results. You can record to multiple separate files, record a single file with combined audio from all parties together, and much more. The Voice Chat template is a fine way to get started, but Audio Hijack is extremely flexible. If you turn this setting off, both audio sources will be captured together in stereo. This is controlled by the Split between channels setting. The local audio (from your microphone) will be placed on the left channel, with the remote audio (the other party or parties) on the right. If you do not wish to capture your own audio, unchecking this setting Split audio into separate channels This is controlled by the Include audio input setting. This means your recording will contain both sides of your conversation. The Application block will add audio from the local microphone you’re using, along with the remote party. When a supported voice chat app is set as the source in an Application input block, Audio Hijack will automatically do two things: Include your audio input Default audio capture behaviors Default settings found in the Advanced options of the Application block Just as radio DJs use closed-ear headphones to prevent the audio they’re hearing from leaking in to their microphone, you’ll want to isolate the other parties out of your microphone by using headphones instead of speakers. To prevent echo and feedback loops, it’s best for all parties to wear headphones when speaking over voice chat. This does not affect the recording, only the local playback. Audio to the output device is adjusted by the Channels effect, so that your caller’s audio is heard in both channels and to make sure your microphone audio is not played back through your headphones. This session sends audio to two outputs, a Recorder block and an Output Device block, in parallel. The Template Chooser window will appear, and you can select the Voice Chat template to make a new session with this layout. To get started, click New Session in Audio Hijack’s Home window or select it in the Session menu. We’ve made this easy to do with the Voice Chat session template. One of Audio Hijack’s most popular uses is to capture audio from voice and video chat applications such as Zoom and Skype. It was again created and produced by YouTube and Portal A Interactive, and was the first one to feature a hashtag, in this case #YouTubeRewind. On December 9, 2015, YouTube Rewind: Now Watch Me 2015, referencing Silentó's " Watch Me (Whip/Nae Nae)", was released. The actual Rewind Button was not shown until the end of the video. The flag was run through the sets of The Colbert Report by Big Bird Conan by host Conan O'Brien himself, with Freddie Wong acting as substitute host and Last Week Tonight with John Oliver by Kid President. Its main feature was the YouTube Rewind Button flag, with which YouTubers and other notable personalities run throughout the video. The video was not structured around songs, as in previous years, with more Internet memes and trends used alongside the music. Over 10 songs were mashed-up by DJ Earworm for the video. It was again created and produced by YouTube and Portal A Interactive. On December 9, 2014, YouTube Rewind: Turn Down for 2014, referencing DJ Snake and Lil Jon's " Turn Down for What", was released. What Does 2013 Say? was dedicated to fellow YouTuber Talia Castellano, who died on July 16, five months prior to the release of the video. It also marked the first appearance of PewDiePie in the Rewind series. Jimmy Fallon and The Roots from The Tonight Show made guest appearances. DJ Earworm served as the music producer for the video, mashing up six popular songs of the year. This was the first year that the YouTube Rewind Button was used otherwise, the video was stylistically similar to the 2012 video. The video was created and produced by YouTube and Portal A Interactive. The video also made prominent use of Psy's " Gentleman", however, following a copyright claim from the artist, the video was amended in 2015 to remove the song. On December 11, 2013, YouTube Rewind: What Does 2013 Say?, referencing Ylvis' " The Fox (What Does the Fox Say?)", was released. The video starts with the text "Nothing is more powerful than a video whose time has come" the final two words change to "is 2012.", with an accompanying string instrument sound, resembling the introduction of Kony 2012, a viral documentary film aired earlier that year.Ģ013 The YouTube Rewind button with the ⏪ symbol was introduced in 2013. It was created and produced by YouTube and Seedwell. Rewind YouTube Style 2012, referencing Psy's " Gangnam Style", was released on December 17, 2012. In 2012, YouTube's Rewind videos changed to featuring several popular YouTubers the most popular music videos, and videos breaking news and internet memes from the year. Like in 2010, it featured another top ten most popular videos of the year on YouTube. It was created and produced by YouTube and Portal A Interactive, and features Rebecca Black, whose music video of her song " Friday" had gone viral in March of that year, as the host. On December 20, 2011, YouTube Rewind 2011 was uploaded. It was uploaded on two channels: YouTube Trends on the first day, and YouTube Spotlight on the second. On December 13, 2010, the first YouTube Rewind was uploaded, titled 2010 YouTube Rewind: Year in Review and featured the top ten most popular videos of the year on YouTube. From 2011 onwards, the Rewind videos have only been uploaded to the YouTube Spotlight channel, now known as just YouTube, with additional behind-the-scenes content. In 2010, YouTube began creating and producing Rewind videos with the help of Seedwell and Portal A Interactive. The first Rewind was created by YouTube in 2010 and featured a list of the 50 most popular YouTube videos of that year. YouTube forwent producing a Rewind installment for 2020, and announced the following year that the series would be discontinued. The next installment, YouTube Rewind 2019: For the Record, also had a poor reception from viewers. The 2018 installment of the series, YouTube Rewind 2018: Everyone Controls Rewind, was panned by critics, YouTubers and viewers alike, garnering over 10 million dislikes in its first two weeks, and becoming the most disliked video of all time on YouTube. The series' annual installments were uploaded onto YouTube's official channel. The videos were an overview and a recap of each year's viral videos, events, trends, and music. YouTube Rewind (stylized as YouTube ЯEWIND) was an annual video series that was produced and created by the American video platform YouTube and Portal A Interactive from 2010 to 2019. |
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